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Twistdx Launches TwistAmp, DNA Amplification Kit Based On RPA

Twistdx has launched TwistAmp product range, based on Recombinase Polymerase Amplification (RPA). Concurrently, Twistdx also introduced the Twista portable, real-time fluorometer, an easy-to-use RPA reader.

The Twista portable real-time fluorometer is a customised platform containing proprietary fluorescent probe systems, developed by the company to accurately monitor RPA reactions.

Although seamlessly integrated with the Twista device, TwistAmp kits can be used in combination with assay platforms, such as conventional analysis tools (on agarose gels), dipsticks, as well as fluorescence plate readers and real-time PCR machines.

Niall Armes, CEO of Twistdx, said: “Our TwistAmp kit offers researchers a flexible and cost-effective solution to achieve DNA amplification in significantly less time. With laboratory analysis a critical but often time-consuming aspect of biomedical research, we believe these new research tools provide our customers with a viable alternative to PCR, which although very effective is costly to access and time consuming.”

“In particular, real-time PCR devices are very expensive; a laboratory could purchase multiple Twista devices for the same price. Field researchers may also be able to easily perform their measurements in a mobile setting as TwistAmp enzyme and nucleotide mixes are provided in a freeze-dried form that demonstrates good stability at ambient temperatures. The Twista device will be available with portable battery pack and standalone software,” he added.