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SAIC-Frederick, Biomatrica collaborate to improve molecular analysis of tumors

SAIC-Frederick and Biomatrica have entered into a technology collaboration to improve molecular analysis of tumors in cancer research.

The collaboration was developed under the Advanced Technology Partnerships Initiative (ATPI) of the National Cancer Institute (NCI).

SAIC-Frederick is the operations and technical support contractor for NCI’s federal national laboratory and facilitates partnerships for the ATPI, which aims to move basic research findings more rapidly into the clinic to benefit patients.

Under the collaboration, SAIC-Frederick researchers at the Laboratory Animal Sciences Program will explore integration of proprietary reagents from Biomatrica into molecular pathology workflows.

The objective is to increase efficiency and integrity of RNA isolated from histological samples in cancer studies.

Laboratory Animal Sciences Program Histology Section director Larry Sternberg said the collaboration with Biomatrica improves isolation of nucleic acids from histological samples, particularly very labile RNA molecules.

Biomatrica president, CSO and founder Rolf Muller said they have developed formulations that protect nucleic acids (RNA and DNA) in blood, tissue, cell lines, saliva, biopsy material at room temperature with better performance than traditional ultra-cold temperature systems.