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OTS collaborates with Duke University over LifeCradle HR device

Organ Transport Systems (OTS), a subsidary of Allezoe Medical, has agreed to provide LifeCradle HR device for donor heart preservation to the research team at Duke University Medical Center in Durham, NC, to evaluate the potential resuscitation of human donor hearts that are currently being discarded.

In addition to researching discarded human hearts, the Duke cardiac transplant team is conducting a series of swine experiments.

In the recently initiated study, the Duke team is examining the results when the donor swine heart is stopped for a period of time, then perfused in the OTS LifeCradle for a couple hours, and then finally transplanted in a recipient swine for validation of cardiac function.

Duke Translational Research Institute has funded principal investigators Valentino Piacentino and Carmelo Milano to support the project.

OTS Research & Regulatory Affairs EVP Thomas Franklin said if discarded hearts can be usable, providing additional hearts for transplantation, this research has the potential to add a completely new dimension to the solutions they are working on to offer the medical community and its growing waitlist of patients in desperate need of a heart transplant.

The Duke research project is entitled Resuscitation & evaluation of human delayed cardiac death (DCD) donor hearts on an ex vivo perfusion apparatus.