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ForteBio Rolls Out Octet QK(e) Instrument For Small Proteins, Peptides Analysis

ForteBio has launched next generation initial eight-channel Octet QK instrument Octet QK(e) instrumentation system that provides increased sensitivity, enabling analysis of small proteins and peptides.

ForteBio claimed that Octet QK(e) system would enable biosensors to be re-racked, for increased workflow flexibility and cost savings.

ForteBio has also introduced latest Anti-Penta-HIS (HIS) biosensors for label-free quantitation of HIS-tagged proteins. The new ‘dip and read’ biosensor comes with the specific Qiagen Penta-HIS antibody pre-immobilized on the surface and is ready to use on ForteBio’s Octet instruments for specific detection and quantitation of HIS-tagged proteins.

ForteBio’s Octet platform is based on the company’s BioLayer Interferometry (BLI) technology, which uses optical biosensors to measure multiple interactions in parallel, without the use of detection agents. The Octet platform consists of 8- and 16-channel instruments that accommodate 96- and 384-well assay formats. All Octet biosensors are designed to simplify quantitation and kinetic characterization by eliminating throughput limitations of traditional SPR-based systems.

The Octet biosensors are disposable, configured in a standard microplate format and are coated with a proprietary biocompatible matrix that is uniform, non-denaturing and has minimal non-specific binding.

Christopher Silva, vice president of marketing of ForteBio, said: “Since its introduction in 2005, our Octet QK product has gained popularity among life science researchers seeking a label-free system that offers increased ease-of-use, sensitivity, throughput and affordability for quantitation of proteins and kinetic characterization of biomolecular binding interactions.

“Our new Octet QK(e) system offers all of these benefits, plus greater sensitivity and a wider dynamic range, due to its two acquisition-rate settings and higher-performance spectrometer. The system’s increased sensitivity is particularly important for researchers analyzing lower molecular weight proteins and peptides. And, because it also allows biosensors to be re-racked at the end of an experiment, the Octet QK(e) system provides a significant value over other label-free systems.”