Calcivis, a medical devices company, has announced that its Calcivis caries activity imaging system has been granted a CE Mark in Europe.
The Calcivis caries activity imaging system is a sophisticated medical device and consumable combination designed to transform the assessment and management of dental caries (tooth decay).
It involves a unique, proprietary bioluminescence approach combined with a specialized imaging device which allows accurate detection and visualization of demineralization by imaging free calcium ions at the tooth surface; a caries lesion which is actively demineralizing is more likely to progress and lead to cavitation.
Calcivis CEO Adam Christie noted the granting of a CE Mark is a landmark for Calcivis.
"Our system will, for the first time, allow the real-time detection and visualisation of calcium ions released by demineralising caries lesions in routine dental practice. This has the potential to allow for tailored, rational, evidence-based treatment in line with dental best practice.
"We believe there will be significant demand for our technology and are now working towards full commercialization," Christie added.
The Calcivis caries activity imaging system is an in-clinic device which combines a sensitive intraoral camera and application technology to deliver a precise amount of disclosing solution, containing a photoprotein, onto the tooth surface.
The photoprotein binds calcium ions and emits a blue light signal proportional to the amount of calcium present. This exquisitely sensitive chemiluminescent system produces a demineralization map of the tooth. The resulting images provide a focus for discussion with patients about their caries management program and the development of a tailored, rational, evidence-based treatment in line with dental best practice.