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Innovative Injection and Blow Moulding for Pharmaceutical Dosing

At Interpack in Dusseldorf, Germany, on May 12 to 18, visitors to the Medisize Corporation stand saw product samples with 2.5 ml dosage capacity that demonstrated a dosing system which has been developed for pharmaceutical liquids that is convincingly more comfortable to handle, straightforward and safe to use.

0The 2K Dosing System is used in connection with orally taken remedies and liquids such as cough linctuses, liquid medication for the treatment of stomach and intestinal ailments, analgesic treatments, vitamins, tonics and circulation compounds, as well as psychotropic drugs, to be taken orally. The system is available for use with hygiene liquids, such as mouthwashes and also for liquid foodstuffs that have to be administered in precise dosages. The two principal components are the dosing head and closure. At the closure opening point the precisely measured liquid reaches the dosing head – to an accuracy of +/- 5 percent.

The Head of Development at Medisize, Dieter Veit, explains the patented system. "After a year of development and prototype mould making, we have perfected a dosing system ready for the market which operates according to the principal of vacuum pressure delivery. By turning the screw closure the dosage head is filled with exact precision. It was our aim to dispense with awkward and imprecise administration implements such as spoons, measuring cups, and bottle caps. One turn and filling is perfect."

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Fewer component parts contribute to increased safety levels and lower costs for potential customers, primarily pharmaceutical companies, in Europe and further afield. Depending on customer specifications, the dosing head can be adapted to dosage volumes between 1 ml to 20 ml. Child safety locking, TE original closure and special geometries are available as optional extras. Currently, the bottle or container sizes correspond to the system and comprise of volumes up to 750 ml. Depending on the application, Medisize can produce the relevant screw closures and dosing heads, injection-moulded in either H DPE or PP.

The bottles/containers can be blowmoulded in either PET, LDPE or H DPE. The moulds are applied using hot runner technology and usually have up to 32 cavities. BDE-documented quality and product safety are guaranteed under clean-room conditions class 7/8. QM certification, ISO and customer re-audits are carried out at regular intervals in addition to frequent quality examinations, batch tests and sampling.